Biosciences

Faster and smarter workflows in:

Single-cell omics, combinatorial screenings, next-generation sequencing, proving monoclonality for cell line development and revolutionizing microscopy.

CUSTOMER CASE
Precise and sensitive tools for
COVID-19 monitoring

“We were able to easily create new workflows for PCR and NGS applications and I highly recommend this system for all labs running high-throughput assays that require complex liquid dispensing schemes, as well as those aiming to lower assay costs by reducing reagent volumes.”

 

Nicola Crosetto, PhD

What is biosciences?

Molecular biology and multi-omics are fast-growing fields with ever increasing requirements for higher throughput and automation. The business area Biosciences provide user-friendly instruments that allow for the gentle handling of cells and rare samples, rapid transfer of liquids and reagents as well as downstream analysis platforms to gain valuable insights from experiments. Bringing efficiency and speed to multiple application areas.

Combining the technologies of the BICO companies CYTENA, DISPENDIX, CYTENA BPS and Discover Echo, the business area offer easy-to-use technologies that facilitate faster and smarter workflows in single-cell omics, combinatorial screenings, next-generation sequencing, proving monoclonality for cell line development and revolutionizing microscopy.

Application areas

Enabling highly cost-efficient single-cell omics workflows – Currently one of the most dynamic research fields and a keystone to generate a better understanding of many diseases, such as cancer.
Optimizing cell line development workflows – An essential step in many emerging fields such as cell and gene therapy.
Offering speed and efficiency to labs in order to bring drugs to the market at an unseen speed.
CUSTOMER CASE
Precise and sensitive tools to
Promote organ regeneration
Given the challenges of combating the COVID-19 pandemic, scientists in both research and diagnostic environments are looking to optimize their workflows for crucial time and cost savings.  

An influential example is a study conducted by Dr. Nicola Crosetto’s lab at Karolinska Institutet, in which the I.DOT (Immediate Drop-on-demand Technology) liquid handler was used to automate and streamline a versatile technique (COVseq) for preparing multiplex DNA sequencing libraries from low-input samples with high accuracy, speed and significant reductions in liquid reagent volumes.

The study revealed that the COVseq technique can be easily applied to ongoing pandemic genomic surveillance and adapted to monitor other pathogens such as influenza viruses. In addition, an analysis of costs showed that the technique could be used to sequence thousands of samples per week at less than $10 per sample, including library preparation and sequencing costs.

An influential example is a study conducted by Dr. Nicola Crosetto’s lab at Karolinska Institutet, in which the I.DOT (Immediate Drop-on-demand Technology) liquid handler was used to automate and streamline a versatile technique (COVseq) for preparing multiplex DNA sequencing libraries from low-input samples with high accuracy, speed and significant reductions in liquid reagent volumes.

The study revealed that the COVseq technique can be easily applied to ongoing pandemic genomic surveillance and adapted to monitor other pathogens such as influenza viruses. In addition, an analysis of costs showed that the technique could be used to sequence thousands of samples per week at less than $10 per sample, including library preparation and sequencing costs.

Read more on cellink.com →

“We were able to easily create new workflows for PCR and NGS applications and I highly recommend this system for all labs running high-throughput assays that require complex liquid dispensing schemes, as well as those aiming to lower assay costs by reducing reagent volumes.”

 

Nicola Crosetto, PhD

Biosciences companies

Founded in 2014, CYTENA deliver automated and highly efficient lab workflows for improved cell line development, microbiome, live cell imaging, liquid handling and omics applications that enable new discoveries in areas such as drug development and health care research. The CYTENA instruments are used in the cell line development workflows at a majority of the worlds top pharmaceutical companies.

Focuses on offering bioprocess solutions for, but not limited to, pharmaceuticals and top research institutes. In close collaboration with leading academic institutes and industrial companies in researching, development, and application, CYTENA BPS bring their novel and comprehensive product into the global bioprocess market.
By providing the finest liquid handling technology to scientists and lab technicians around the world, DISPENDIX enables new discoveries in areas such as drug development, diagnostics and synthetic biology. DISPENDIX GmbH, started out in 2016 as a spin-off from the Fraunhofer Institute for Manufacturing Engineering and Automation (IPA) in Stuttgart, Germany.
Discover Echo is built on the vision to “rethink traditional microscope design”. Every aspect of workflow, usability, and performance have been pushed to create a more modern and powerful product.