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- March 4, 2025
- 9:47 am
Introducing the CYTENA Biologic Manufacturing Cell Line Tracker
Introducing the CYTENA Biologic Manufacturing Cell Line Tracker
A wide variety of cell lines are utilized throughout the biotechnology industry for a variety of different manufacturing purposes, and it can be difficult to identify the optimal cell line for your specific need. To help make your decision easier, we created a database that includes all the cell lines used in biotech manufacturing alongside a detailed profile of their key characteristics.
What’s in the Tracker?
The tracker contains information on every cell line – mammalian, insect, bacterial, or yeast – that is currently used in biologic manufacturing. This includes both cell lines used for production purposes and cell lines used for research that influences production. The following information is covered for each cell line (where applicable):
- Cell Line: The most commonly used name for the cell line, typically an abbreviation.
- Alternate Names: Any additional names by which the cell line is commonly known.
- Variants: Subpopulations or modified versions of the original cell line that are commonly used, exhibiting unique characteristics that make them distinct.
- Species/Strain: In the case of mammalian and insect cell lines, this refers to the species from which they originated. For bacterial and yeast cell lines, this refers to the strains of bacteria and yeast that are typically used in biologic manufacturing.
- Tissue of Origin: The specific tissue from which the cell line was derived.
- Adherent/Suspension: Determines whether the cells are typically grown as a suspension culture, an adherent culture, or if either format can be used depending on the application.
- Production/Research: Determines whether the cell line is typically used for production purposes, research purposes, or at both levels of manufacturing.
- Applications: Processes for which the cell line is typically used, e.g. recombinant protein production.
- Drug/Product Examples: Drug types that are produced using the cell line, including examples of marketed drugs to which the cell line has contributed.
- Vendors: Distributors from which the cell line can be acquired.
Why Use the Tracker?
Biotechnology is rapidly expanding, and this growth is being accompanied by an increase in the number of cell lines that are being used throughout the industry. This is creating a situation in which optimization is becoming both more important and more difficult, with an array of different cell lines to choose from.
This tracker acts as a straightforward and comprehensive guide that can help to identify the optimal cell line for your production or research requirements. As such, whether you are planning a new production line or looking to refine an existing process, this tracker is an invaluable tool when choosing which cell line(s) to use.
How to Use the Tracker
Scroll through the tracker to gain an understanding of the different cell lines that are currently being used throughout the industry. If you are searching for something specific, perhaps a cell line that can be used to produce adenoviral vectors, simply sort by the relevant column and discover the cell lines that meet your criteria.
How Do We Populate the Tracker?
We scour diverse authoritative sources to ensure this tracker is as comprehensive as possible, including:
- Cell line databases
- Company websites
- Research papers
- Literature reviews
Where possible, we verify the information using multiple sources, with cell line databases and company websites taking precedence.
How Often is it Updated?
We update the tracker once-twice yearly to make sure you never miss a beat.
Did we miss something? Let us know what you’d like to see added to the tracker.
How CYTENA Instruments Accelerate Biologic Manufacturing
At CYTENA, we support companies developing and manufacturing novel biologics. Our UP.SIGHT is a dual single-cell dispenser and imager that streamlines cell line development and derisks workflows by providing >99.99% probability of clonal derivation. This instrument uses microfluidics to ensure gentle dispensing, minimizing cell stress and enabling you to achieve >80% cloning efficiency.
If you want to join the automation revolution that so many top companies already benefit from, then the C.STATION from CYTENA is your ultimate solution. The C.STATION provides end-to-end automation for cell line development that integrates confluency screening, antibody titer measurements, and much more. This means you get pure, high-performing cell lines quickly, while freeing up time and resources for other tasks.
Ready to supercharge your biologic development? Take a look at the CYTENA cell line tracker, find your optimal cell line, and then visit our product page to discover how our comprehensive suite of instruments can help streamline your workflows.
Disclaimer: While we endeavor to include all cell lines currently used in biologic manufacturing, some may have been omitted by mistake.
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