BIO CELLX
Automated 3D Cell Culture. Simplified.
![BIO-CELLX-Image-Hero.jpg BIO-CELLX-Image-Hero.jpg](https://bico.com/wp-content/uploads/elementor/thumbs/BIO-CELLX-Image-Hero-qq3ucrfiq1qyfoidnqbgr75mmqr9ins9nn8wcu2e6w.jpg)
Upscaled automation
The high-throughput, fully automated biodispensing solution that leverages BIOPOD (bioprinting on demand) technology with pre-set and pre-validated protocols to bring the power of 3D cell biology to your benchtop.
![Easy-To-Operate-Icon.png Easy-To-Operate-Icon.png](https://bico.com/wp-content/uploads/elementor/thumbs/Easy-To-Operate-Icon-qq3uctaykqay656xx80hxbg0v7rych2n84txvxv08w.png)
Easy to operate
The platform leverages BIOPOD technology by combining a state-of-the-art instrument with pre-validated, built-in protocols and material mixing cartridges to offer a solution that is easier to use than any other system on the market: a plug-and-play user experience.
![No-Cell-Sedimentation.png No-Cell-Sedimentation.png](https://bico.com/wp-content/uploads/elementor/thumbs/No-Cell-Sedimentation-qq3ucv6myeditd47m8tr2ayy1ziorva3we4wuhs7wg.png)
Automated bioink preparation
Cartridges enable the automated mixing of cells with hydrogels gently and homogenously at the push of a button. This novel approach ensures high cell viability and automates neutralizing collagen.
![Effortless-Hydrogel-Extrusion.png Effortless-Hydrogel-Extrusion.png](https://bico.com/wp-content/uploads/elementor/thumbs/Effortless-Hydrogel-Extrusion-qq3uctaykqay656xx80hxbg0v7rych2n84txvxv08w.png)
Effortless hydrogel extrusion
Each of the three cartridge stations offers precise temperature control ranging from 0°C to 60°C, allowing for hassle-free printing of ECM hydrogels and bioinks like Collagen, GelMA, and GelXA.
![Precise-and-reproducible.png Precise-and-reproducible.png](https://bico.com/wp-content/uploads/elementor/thumbs/Precise-and-reproducible-qq3ucv6myeditd47m8tr2ayy1ziorva3we4wuhs7wg.png)
Precise and reproducible
A high-precision positive displacement extrusion system provides reproducible results every single time, regardless of the dispensed material.
![Droplet-Blue.png Droplet-Blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Droplet-Blue-qq3uctaykqav3nlart7mn92it50bnl9yu409kzvri8.png)
Droplet
- Tumor spheroids
- Tumor spheroids (co-culture)
- Organoids
- Immuno-oncology
![DropletInDroplet-Blue.png DropletInDroplet-Blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/DropletInDroplet-Blue-qq3uctaykqav3nlart7mn92it50bnl9yu409kzvri8.png)
Droplet-in-droplet
- Cancer invasion
- Cancer invasion (co-culture)
![Grid-Blue.png Grid-Blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Grid-Blue-qq3ucu8srkc5f9jxmbm97qtzeivovadp68nr29udc0.png)
Grid
- Bone metastasis
![Droplets-Circle-Blue.png Droplets-Circle-Blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Droplets-Circle-Blue-qq3uctaykqav3nlart7mn92it50bnl9yu409kzvri8.png)
Droplet-in-circle
- Chimeric tumoroid
By scientists, for scientists
Pre-validated protocols for easy use
Working with pre-validated protocols allows you to produce 3D cellular models with minimal effort. The pre-loaded detailed plans cover everything from construct geometry to biomaterial selection to dispensing settings. Additionally, each protocol includes step-by-step instructions for upstream and downstream analysis, so there are no bottlenecks in your workflow as you transition to 3D cell culturing.
Select from protocols pre-loaded on your system or from an ever-growing database of protocols offered as cloud-based updates.
Select from protocols pre-loaded on your system or from an ever-growing database of protocols offered as cloud-based updates.
Benefits
![High-reproducibility-blue.png High-reproducibility-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/High-reproducibility-blue-qq3ucu8srkc6g3f5c4jvn3mhf7swfkz9awxn5x648w.png)
High
reproducibility
![high-cellular-viability-blue.png high-cellular-viability-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/high-cellular-viability-blue-qq3ud1ria8mh0z4847sw71q66aru55t3zy5j04uyv4.png)
High cellular viability
![High-Throughput-blue.png High-Throughput-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/High-Throughput-blue-qq3ucu8srkc6g3f5c4jvn3mhf7swfkz9awxn5x648w.png)
High
throughput
![Echo-microscope-revolver-blue.png Echo-microscope-revolver-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Echo-microscope-revolver-blue-qq3uctaykqaw4hgihm592lv0ttxj7vviysa5on7if4.png)
![Echo-microscope-revolver-blue.png Echo-microscope-revolver-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Echo-microscope-revolver-blue-qq3uctaykqaw4hgihm592lv0ttxj7vviysa5on7if4.png)
![Echo-microscope-revolver-blue.png Echo-microscope-revolver-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Echo-microscope-revolver-blue-qq3uctaykqaw4hgihm592lv0ttxj7vviysa5on7if4.png)
Better downstream imaging
![High-Throughput-blue.png High-Throughput-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/High-Throughput-blue-qq3ucu8srkc6g3f5c4jvn3mhf7swfkz9awxn5x648w.png)
![High-Throughput-blue.png High-Throughput-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/High-Throughput-blue-qq3ucu8srkc6g3f5c4jvn3mhf7swfkz9awxn5x648w.png)
![High-Throughput-blue.png High-Throughput-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/High-Throughput-blue-qq3ucu8srkc6g3f5c4jvn3mhf7swfkz9awxn5x648w.png)
High
throughput
![Cost-effective-blue.png Cost-effective-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Cost-effective-blue-qq3uctaykqaw4hgihm592lv0ttxj7vviysa5on7if4.png)
![Cost-effective-blue.png Cost-effective-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Cost-effective-blue-qq3uctaykqaw4hgihm592lv0ttxj7vviysa5on7if4.png)
Cost
effective
![Time-speed-desk.png Time-speed-desk.png](https://bico.com/wp-content/uploads/elementor/thumbs/Time-speed-desk-qq3ucx2bc2g1exb1vnrrckwv7df02oagbaw3lr1xq8.png)
![Time-speed-desk.png Time-speed-desk.png](https://bico.com/wp-content/uploads/elementor/thumbs/Time-speed-desk-qq3ucx2bc2g1exb1vnrrckwv7df02oagbaw3lr1xq8.png)
Time
savings
![Echo-microscope-revolver-blue.png Echo-microscope-revolver-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Echo-microscope-revolver-blue-qq3uctaykqaw4hgihm592lv0ttxj7vviysa5on7if4.png)
![Echo-microscope-revolver-blue.png Echo-microscope-revolver-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Echo-microscope-revolver-blue-qq3uctaykqaw4hgihm592lv0ttxj7vviysa5on7if4.png)
![Echo-microscope-revolver-blue.png Echo-microscope-revolver-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Echo-microscope-revolver-blue-qq3uctaykqaw4hgihm592lv0ttxj7vviysa5on7if4.png)
Better downstream imaging
From bioprinting to biodispensing
Further reducing the barriers to 3D cell culture for reproducible and fully automated workflows
Whereas bioprinters produce complex models, biodispensers create simpler models and droplets while greatly increasing throughput.
Biodispensing makes the creation of biomimetic models accessible to everyone. By focusing on droplets and simpler geometries, it ensures reproducibility and increases the speed at which models are created. Furthermore, biodispensing requires much less input from the user, allowing for an unparalleled plug-and-play experience.
Biodispensing makes the creation of biomimetic models accessible to everyone. By focusing on droplets and simpler geometries, it ensures reproducibility and increases the speed at which models are created. Furthermore, biodispensing requires much less input from the user, allowing for an unparalleled plug-and-play experience.
Models
- Single-layer structures
- Droplet in droplet
- Droplet
Features
- Pre-validated protocols
- Precise and reproducible
- Plug-and-play experience
Materials
- Collagen
- GelMA
- GelXA
![](https://bico.com/wp-content/uploads/2022/03/BIO-CELLX-with-Software-1024x575.jpg)
![](https://bico.com/wp-content/uploads/2022/03/BIO-CELLX-with-Software-1024x575.jpg)
Biodispensing at the push of a button
BIO CELLX Studio
Maximizing walk-away capabilities through the power of automation.
A brand-new intuitive version of DNA Studio guides users through the entire process, from setting up the system to selecting one of the pre-set and pre-validated protocols.
No training required.
![Protocol-blue.png Protocol-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Protocol-blue-qq3ucv6myedcodwxbf80i67xxtzfe3or4chk8ltqf4.png)
![Protocol-blue.png Protocol-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Protocol-blue-qq3ucv6myedcodwxbf80i67xxtzfe3or4chk8ltqf4.png)
No code solution
An intuitive user interface requires no prior coding experience
![Modeling-blue.png Modeling-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Modeling-blue-qq3ucu8srkc2cryagwtdxoghcg426el0s7u2rbv4lc.png)
![Modeling-blue.png Modeling-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Modeling-blue-qq3ucu8srkc2cryagwtdxoghcg426el0s7u2rbv4lc.png)
No modeling required
Built-in 3D models mean no time wasted in CAD software.
![Touchscreen-blue.png Touchscreen-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Touchscreen-blue-qq3ucx2bc2fxblu70g19n5qv4lq5thw7slsj75qy2o.png)
![Touchscreen-blue.png Touchscreen-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Touchscreen-blue-qq3ucx2bc2fxblu70g19n5qv4lq5thw7slsj75qy2o.png)
Touchscreen optimized
It has never been easier to operate an interface with a gloved finger.
![Flexible-well-selection.png Flexible-well-selection.png](https://bico.com/wp-content/uploads/elementor/thumbs/Flexible-well-selection-qq3ucu8srkc2cryagwtdxoghcg426el0s7u2rbv4lc.png)
![Flexible-well-selection.png Flexible-well-selection.png](https://bico.com/wp-content/uploads/elementor/thumbs/Flexible-well-selection-qq3ucu8srkc2cryagwtdxoghcg426el0s7u2rbv4lc.png)
Flexible well selection
Selecting single wells or columns in a plate is as easy as swiping a finger.
![Effectivity-blue.png Effectivity-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Effectivity-blue-qq3uctaykqas15znmeerd6p0r28oyphag36la1wirk.png)
![Effectivity-blue.png Effectivity-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Effectivity-blue-qq3uctaykqas15znmeerd6p0r28oyphag36la1wirk.png)
From one to thousands of samples
The interface will guide you through the process of filling multiple plates.
![Customer-profile-blue.png Customer-profile-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Customer-profile-blue-qq3uctaykqas15znmeerd6p0r28oyphag36la1wirk.png)
![Customer-profile-blue.png Customer-profile-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Customer-profile-blue-qq3uctaykqas15znmeerd6p0r28oyphag36la1wirk.png)
Customer profiles
Integration with MyCELLINK account allows the protocols to be used on multiple instruments.
![Adjustable-droplet-blue.png Adjustable-droplet-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Adjustable-droplet-blue-qq3ucpjlte5mqq548cs937n6dir83x2d3kkncy23gg.png)
![Adjustable-droplet-blue.png Adjustable-droplet-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/Adjustable-droplet-blue-qq3ucpjlte5mqq548cs937n6dir83x2d3kkncy23gg.png)
Adjustable droplet size
Select the size of droplets in line with your goals and downstream analysis methods.
![camera-view-blue.png camera-view-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/camera-view-blue-qq3ud0to3el2m1oqehnrx4spi57moab554eh49ldds.png)
![camera-view-blue.png camera-view-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/camera-view-blue-qq3ud0to3el2m1oqehnrx4spi57moab554eh49ldds.png)
Camera view
Observe the samples as they get dispensed.
Click to see the system in action
A bio-convergence workflow
Developing The Next Generation of Cancer Therapeutics
![High-reproducibility-blue.png High-reproducibility-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/High-reproducibility-blue-qq3ucu8srkc7gxad1xhi2gezfwq3zvktfl7j9khv5s.png)
![High-reproducibility-blue.png High-reproducibility-blue.png](https://bico.com/wp-content/uploads/elementor/thumbs/High-reproducibility-blue-qq3ucu8srkc7gxad1xhi2gezfwq3zvktfl7j9khv5s.png)
1. Cell counting
Kick-start your 3D cell culture workflow by ensuring cell health and density. The CASY cell counter, distributed by CYTENA, can be used to assess cell viability in a label-free method with as little as 10 μL.
![BIO-CELLX-Icon.png BIO-CELLX-Icon.png](https://bico.com/wp-content/uploads/elementor/thumbs/BIO-CELLX-Icon-qq3ucrfa7289flstczgr2wr3locdnwgy16feismsxs.png)
![BIO-CELLX-Icon.png BIO-CELLX-Icon.png](https://bico.com/wp-content/uploads/elementor/thumbs/BIO-CELLX-Icon-qq3ucrfa7289flstczgr2wr3locdnwgy16feismsxs.png)
2. 3D model generation
Effortlessly mix cells into tailored biomaterials like TeloCol-10 (bovine collagen) provided by Advanced BioMatrix with full integration with the BIO CELLX. Begin 3D model generation with the click of a button thanks to the intuitive BIOPOD technology onboard.
![C.WASH_.png C.WASH_.png](https://bico.com/wp-content/uploads/elementor/thumbs/C.WASH_-qq3ucsd4dw9hpk10rw04soxk5odbr0dk3yj3srxwxs.png)
![C.WASH_.png C.WASH_.png](https://bico.com/wp-content/uploads/elementor/thumbs/C.WASH_-qq3ucsd4dw9hpk10rw04soxk5odbr0dk3yj3srxwxs.png)
3. Plate washer
Ensure ideal cell culture conditions with automated media exchange thanks to CYTENA’s C.WASH system. Remove old media and directly dispense fresh media all while eliminating the risk of contamination.
![idotty.png idotty.png](https://bico.com/wp-content/uploads/elementor/thumbs/idotty-qq3ud1ria8mi1szfu0qimeio6zp1pgeo4mff3s6ps0.png)
![idotty.png idotty.png](https://bico.com/wp-content/uploads/elementor/thumbs/idotty-qq3ud1ria8mi1szfu0qimeio6zp1pgeo4mff3s6ps0.png)
4. Compound dispensing
Begin high-throughput screening by rapidly dispensing different concentrations of drugs and reagents using DISPENDIX’s I.DOT, the premier non-contact liquid handler.
![Cellcyte-X.png Cellcyte-X.png](https://bico.com/wp-content/uploads/elementor/thumbs/Cellcyte-X-qq3uctaykqaw4hgihm592lv0ttxj7vviysa5on7if4.png)
![Cellcyte-X.png Cellcyte-X.png](https://bico.com/wp-content/uploads/elementor/thumbs/Cellcyte-X-qq3uctaykqaw4hgihm592lv0ttxj7vviysa5on7if4.png)
5. Assays and analysis
Harness the power of live cell imaging with CYTENA’s CELLCYTE X. Gather essential insights on cell health, cell count, nuclei count all from inside an incubator. Multiplex your assays by adding cell-friendly reagents like C.LIVE Tox and understand parameters like metabolic activity, apoptosis, and membrane integrity.
![](https://bico.com/wp-content/uploads/2021/09/1Logotype_RGB_Cellink_Neg-1024x256.png)
![](https://bico.com/wp-content/uploads/2021/09/1Logotype_RGB_Cellink_Neg-1024x256.png)
The Leader of 3D Bioprinting
CELLINK is the leading innovator of technologies at the forefront of 3D cell culture, driving to a future where on-demand bioprinted human organs and tissues are a reality.
As a part of the BICO family, CELLINK is working alongside with other companies within the group in engineering, robotics, artificial intelligence, advanced genomics and bioprinting, leveraging the power of Bio-convergence to unlock synergies and offer products that accelerate research and create the future of health.