3D Cell Culture & Bioprinting

3D cell culture and bioprinting technologies enable the creation of physiologically relevant tissues and models that better replicate human biology. By combining biomaterials, cells, and printing systems, these platforms advance research in drug discovery, personalized medicine, and tissue engineering.

PRODUCTS

BIO X6™

Delivering unparalleled bioprinting flexibility with 6 printheads

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BIONOVA X

Direct-in-well, high speed and high resolution 3D bioprinting

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spheroONE

Automated sorting and isolation of single spheroids and organoids

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Materials by Advanced BioMatrix

3D hydrogels, extracellular matrices, reagents, and more

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BIO X™

The go-to bioprinter for academics, researchers and innovators

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LUMEN X™

Experience the standard for benchtop DLP bioprinters

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BIO ONE

Easy-to-use, syringe-based dispensing of hydrogel droplets

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Understanding 3D Cell Culture & Bioprinting

3D cell culture and bioprinting technologies enable the creation of living models that more closely resemble human tissues and organs. By combining precise printing systems with advanced biomaterials, researchers can design constructs with defined geometry, mechanical properties, and biological complexity.

Modern 3D bioprinters make it possible to build detailed tissue models directly within standard labware, or custom geometries, supporting various research needs.

Together with tailored biomaterials that mimic the extracellular matrix, 3D cell culture and bioprinting provide the precision, reproducibility, and biological relevance required for cutting-edge work in tissue engineering, drug discovery, and personalized medicine. Single-spheroid sorting and isolation additionally provide standardized, single 3D models for drug testing assays.

APPLICATIONS

3D In Vitro Models

Develop physiologically relevant 3D models that replicate human tissue structure and function for more predictive in vitro studies.

Tissue Engineering

Fabricate complex, functional tissues by combining cells and biomaterials in controlled architectures for regenerative applications.

Drug Discovery & Toxicology Testing

Use bioprinted tissues to evaluate drug efficacy and safety with improved accuracy compared to traditional 2D cultures.

Personalized Medicine

Create patient-specific tissue constructs to study individual responses to therapies and guide the development of tailored treatments.

Disease Modeling

Reconstruct pathophysiological environments to investigate disease mechanisms and treatment outcomes in a controlled setting.

Material Development

Explore and optimize new bioinks and hydrogels for enhanced biocompatibility, print fidelity, and mechanical performance.

FAQ

What is 3D Bioprinting?

3D bioprinting is the process of fabricating living, three-dimensional structures using cells, biomaterials, and bioinks. By precisely depositing these components layer-by-layer, or even continuously in some light-based systems, it enables the creation of tissue-like constructs for drug discovery research, disease modeling and regenerative medicine.

Traditional 2D cell culture grows cells on flat surfaces, limiting their ability to form native-like structures. 3D cell culture allows cells to interact in three dimensions, leading to more physiologically relevant models that better replicate in vivo conditions.

3D bioprinted tissues mimic human physiology more closely than 2D models, improving the predictability of preclinical testing. This helps researchers identify promising candidates faster, reduce reliance on animal testing, and lower development costs.

Bioinks provide the structural and biochemical environment that supports cell growth and differentiation. Selecting or formulating the right bioink is key to achieving desired printability, cell viability, and tissue functionality.

3D bioprinting encompasses several approaches to suit different research needs. Extrusion-based systems, such as BIO X and BIO X6, deposit bioinks in continuous filaments, offering versatility for a wide range of tissue constructs. Light-based systems, including LUMEN X and BIONOVA X, use digital light processing (DLP) to cure entire layers, or even continuous volumes, of bioink with high resolution and precision. Biodispensing platforms, like BIO ONE, deliver cells and materials in droplets for gentle, highly controlled deposition, ideal for delicate or low-volume applications.

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Get in touch with a BICO expert today to discuss your research goals, explore our innovative solutions, and find the approach that perfectly aligns with your lab’s needs. Whether you’re looking for a quote, a product demo, or technical guidance, our team is here to support you every step of the way.
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